MUSC

MUSC Nursing Jobs

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About Us

Who We Are

With roots in Charlston dating to 1824, the Medical University of South Carolina (MUSC) is the oldest medical school in the South. MUSC now educates more than 3,100 students in six colleges and trains over 950 residents each year. As South Carolina’s only comprehensive academic health system, MUSC has a mission to change what’s possible.

The 31,000 MUSC members are dedicated to delivering the highest-quality and safest patient care while fulfilling the goal of educating and training the next generation of care providers. It’s no wonder that MUSC nursing jobs are in demand. If you are considering one of the many MUSC careers open to dedicated nursing professionals, this is the place to start.

Interested in exploring MUSC jobs? Then you’ll want to know that as a nurse, your voice matters. You can take part in nurse-driven research, or help to improve daily practice by participating in the MUSC shared governance councils. Whether you are a dedicated clinician or are more focused on advancing the future of healthcare through research, there are MUSC jobs that may be a fit for you. You can find what ignites your passion working at:

  • Medical University Hospital Authority (MUHA), which employs care teams across the state
  • Medical University (UNIV), which is the state’s only integrated academic health sciences center
  • MUSC Physicians (MUSC-P), which includes physicians, advanced practice providers, clinicians, and non-clinical staff that provide care in the Charlston area

Whatever your area of expertise or preferred care setting, MUSC nurse jobs are opportunities to explore.

MUSC Nursing Jobs: Benefits

With an operating budget of $7.1 billion dollars and a world-class faculty, MUSC offers a wide variety of career paths and opportunities for nurses. No matter if you are starting out as a new grad RN or are an experienced nurse, you’ll find the culture at MUSC is based on a supportive team environment that ensures collaboration across disciplines.

Nurses can receive benefits and perks commensurate with the level of excellence MUSC maintains, including:

  • Competitive pay
  • Up to $25,00 towards student loan debt annually (for qualified team members)
  • Flexible insurance options, including dental and vision
  • Paid parental leave
  • Retirement plans that are right for you (supplemental or traditional)

Why Choose MUSC Nursing Jobs?

At the Medical University of South Carolina, the values of collaboration, compassion, innovation, integrity, and respect are at the heart of what staff does each day — and this commitment to providing outstanding patient care has been widely recognized. Some of the awards MUSC has received include:

  • #1 ranked hospital in South Carolina (US News, 2014–2024)
  • Magnet Designation (ANCC)
  • America’s Best-in-State Employers (Forbes, 2022)
  • America’s Best Large Employers (Forbes, 2023)
  • Diversity Champion (Insight Into Diversity Magazine, 2023)

Awards and recognition are valuable, but dedicated team members are what truly make a hospital system great. Find out what nursing means to this MUSC team member:

Recent Jobs
LPN Infusion Outpatient Full-time
MUSC

CMA or LPN - Chemotherapy Infusion Clinic (Mt. Pleasant)

MUSC Mount Pleasant, SC
Job Description Summary New Clinic Opening in May of 2026! Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC005552 CHS - East Cooper Oncology (offsite) Pay Rate Type Hourly Pay Grade Health-22 Scheduled Weekly Hours 40 Work Shift Day (United States of America) Job Description CMA Job Summary/Purpose: Under the direct supervision of a Registered Nurse, the Certified Medical Assistant performs multi-skilled activities to support a decentralized patient-centered approach to patient care and achieve desired outcomes. LPN Job Summary/Purpose: Responsible for quality patient care under the direction of a physician or licensed healthcare provider in a clinical practice. Duties to include rooming patients, taking vitals and health history, documenting in an electronic medical record, giving injections and assisting with minor procedures. CMA Minimum Training and Education: High school diploma or equivalent. Completion of an accredited medical assisting program with one year of patient care experience preferred. Basic computer skills required. Current Basic Life Support (BLS) required, either a certification from an American Heart Association (AHA) BLS for Healthcare Providers (or AHA recognized equivalent) or an American Red Cross CPR/AED for Professional Rescuer and Healthcare Provider. Annual competencies are required to be maintained. Possess ability to understand and implement a variety of detailed instructions in the execution of therapeutic procedures and ability to make accurate physical observation of patients. Failure to abide by MUHA policies are subject to disciplinary action, including termination. Employee must possess considerable knowledge of basic medical terminology and human anatomy; ability to understand and implement a variety of detailed instructions in the execution of complex therapeutic procedures; and ability to make accurate physical observation of patients. Must communicate effectively both verbally and in writing. LPN Minimum Training and Education: Graduation from a recognized Licensed Practical Nursing program and licensed as an LPN within the state of South Carolina or a compact state. One year of LPN experience preferred. Current Basic Life Support (BLS) required, either a certification from an American Heart Association (AHA) BLS for Healthcare Providers (or AHA recognized equivalent) or an American Red Cross CPR/AED for Professional Rescuer and Healthcare Provider. CMA Required Licensure, Certifications, Registrations: Must be certified through the American Medical Technologist (AMT) or American Association of Medical Assistants (AAMA) or National Health career Association (NHA) or MedCA as a Certified Clinical Medical Assistant (CCMA), Certified Medical Assistant (CMA), or National Association for Health Professionals (NAHP). Current Basic Life Support (BLS) required, either a certification from an American Heart Association (AHA) BLS for Healthcare Providers (or AHA recognized equivalent) or an American Red Cross CPR/AED for Professional Rescuer and Healthcare Provider. LPN Required Licensure, Certifications, Registrations: Licensed as an LPN within the state of South Carolina or a compact state. Current Basic Life Support (BLS) required, either a certification from an American Heart Association (AHA) BLS for Healthcare Providers (or AHA recognized equivalent) or an American Red Cross CPR/AED for Professional Rescuer and Healthcare Provider. Additional Job Description Physical Requirements: Ability to perform job functions while standing. (Continuous) Ability to perform job functions while sitting. (Continuous) Ability to perform job functions while walking. (Continuous) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work outside in temperature extremes. (Infrequent) Ability to work from elevated areas. (Frequent) Ability to work in confined/cramped spaces. (Frequent) Ability to perform job functions from kneeling positions. (Infrequent) Ability to bend at the waist. (Continuous) Ability to twist at the waist. (Frequent) Ability to squat and perform job functions. (Frequent) Ability to perform "pinching" operations. (Frequent) Ability to perform gross motor activities with fingers and hands. (Continuous) Ability to perform firm grasping with fingers and hands. (Continuous) Ability to perform fine manipulation with fingers and hands. (Continuous) Ability to reach overhead. (Frequent) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to use lower extremities for balance and coordination. (Frequent) Ability to reach in all directions. (Continuous) Ability to lift and carry 50 lbs. unassisted. (Infrequent) Ability to lift/lower objects 50 lbs. from/to floor from/to 36 inches unassisted. (Infrequent) Ability to lift from 36" to overhead 25 lbs. (Infrequent) Ability to exert up to 50 lbs. of force. (Frequent) Examples include: To transfer a 100 lb. patient that can not assist in the transfer requires 50 lbs. of force. For every 100 additional pounds, assistance will be required from another healthcare worker. 20 lbs. of force is needed to push a 400 lb. patient in a wheelchair on carpet. 25 lbs. of force is required to push a stretcher with a patient with one hand. Ability to maintain 20/40 vision, corrected, in one eye or with both eyes. (Continuous) Ability to see and recognize objects close at hand or at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to deal effectively with stressful situations. (Continuous) Ability to work rotating shifts. (Frequent) Ability to work overtime as required. (Frequent) Ability to work in a latex safe environment. (Continuous) Ability to maintain tactile sensory functions. (Continuous) *(Selected Positons) *Ability to maintain good olfactory sensory function. (Continuous) *(Selected Positons) *Ability to be qualified physically for respirator use, initially and as required. (Continuous) (Selected Positions)*. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
CMA Full-time
MUSC

Certified Medical Assistant - Cardiology - MUSCP

MUSC Ladson, SC
Job Description Summary Come join a busy and dynamic Cardiology practice with three locations. We are looking for a dedicated, hard worker and someone who wants to learn to join our practice. We are looking for high performers and team players to apply! Responsible for quality patient care under the direction of a physician or licensed healthcare provider in a clinical practice. Duties to include rooming patients, taking vitals and health history, documenting in an electronic medical record, giving injections and assisting with minor procedures. Entity MUSC Health Partners (MHP) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC005335 CFC COMM MUSC Health Atlantic Cardiovascular Associates Pay Rate Type Hourly Pay Grade Health-21 Scheduled Weekly Hours 40 Work Shift Job Description Ensures accurate calibrations, cleaning and scheduled maintenance of clinical/lab equipment as required by OSHA, DHEC and UMA; tracked by documentation. Maintains and reviews patient records, charts and any other pertinent information, communicating as appropriate. Document test and exam results. Communicates plan of care to the patient including formal development of patient education materials as necessary. Maintains exam room supplies, instruments and cleanliness of patient care environment, as required by OSHA, DHEC and UMA. Maintains timely flow of patient, assists with scheduling of appointments and referrals based on urgency and availability. Screens patients for appropriate information and provides patient education as appropriate for diagnosis and treatment. Observes, records and reports patient's physical and psychosocial condition, reactions to medication and treatments to physician. Responds to and triages phone calls. Call in orders appropriately as ordered by physician. Instructs patient, as ordered by the physician, regarding treatment and/or medication. Responsible for monitoring and distribution of medication including samples and controlled substances. Triages patients and prepares for physician exams and procedures. Assists with exam, procedures and treatments as necessary. Instructs patients in collection of samples and tests. Administers prescribed treatments and tests as ordered by the physician. Additional Job Description CMA I Required Minimum Training and Education: High school diploma or equivalent. Completion of an accredited medical assisting program with one year of patient care experience preferred. CMA Required Licensure, Certifications, Registrations: Must be certified through American Medical Technologist (AMT), American Association of Medical Assistants (AAMA), National Healthcareer Association (NHA), National Association of Healthcare Professionals (NAHP), Medical Career Assessments (MedCA), National Center for Competency Testing (NCCT), or National Association for Health Professionals (NAHP). Current American Heart Association (AHA) Basic Life Support (BLS) certification or American Red Cross BLS for Healthcare Providers certification is required. LPN I Minimum Training and Education: Graduate from an accredited Practical Nurse program. Licensed as an LPN within the state of South Carolina or a compact state. LPN Required Licensure, Certifications, Registrations: Current South Carolina LPN License or compact state license. Current American Heart Association (AHA) Basic Life Support (BLS) certification or American Red Cross BLS for Healthcare Providers certification is required. Physical Requirements: Continuous requirements are to perform job functions while standing, walking and sitting. Ability to bend at the waist, kneel, climb stairs, reach in all directions, fully use both hands and legs, possess good finger dexterity, perform repetitive motions with hands/wrists/elbows and shoulders, reach in all directions. Ability to be qualified physically for respirator use, initially and as required. Maintain 20/40 vision corrected, see and recognize objects close at hand and at a distance, work in a latex safe environment and work indoors. Frequently lift, lower, push and pull and/or carry objects weighing 50 lbs (+/-) unassisted, exert up to 50 lbs of force, lift from 36” to overhead 25 lbs. Infrequently work in dusty areas and confined/cramped spaces. If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
LPN OR Full-time
MUSC

Licensed Practical Nurse or Certified Medical Assistant

MUSC Orangeburg, SC
Job Description Summary We are seeking a dedicated and adaptable member (LPN, CMA, or RMA) to join our Wagener Mobile Health Unit. This role provides a balance of clinical support, clerical duties, and operational maintenance in a dynamic, community-based healthcare setting. The ideal candidate is compassionate, detail-oriented, and thrives in a fast-paced, mobile care environment. Entity MUSC Community Physicians (MCP) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC005638 MCP - Orangeburg - Wagener Mobile Health Unit Pay Rate Type Hourly Pay Grade Health-25 Scheduled Weekly Hours 36 Work Shift Job Description Key Responsibilities Clinical Support – 50% Perform patient intake, including vital signs, history, and medication reconciliation. Administer immunizations, medications, and point-of-care testing under provider supervision. Assist providers with examinations, procedures, and treatments. Maintain infection control and safety standards in mobile settings. Provide patient education regarding medications, treatments, and follow-up care. Clerical & Administrative Duties – 30% Schedule and confirm patient appointments and manage the mobile clinic calendar. Register patients, verify insurance, and ensure accurate demographic entry. Document clinical information in the electronic health record (EHR). Respond to patient inquiries and route communications as appropriate. Support collection of patient satisfaction data and program outcomes. Mobile Unit Operations & Maintenance – 20% Set up and break down exam rooms and workstations daily. Restock medical and office supplies regularly. Perform routine equipment checks; report maintenance or repair needs. Maintain vehicle cleanliness and coordinate safety inspections. Safely handle and transport biohazard waste per regulations. Qualifications Current licensure/certification as LPN, CMA, or RMA required. Basic Life Support (BLS) certification required. Previous experience in ambulatory, community health, or mobile care preferred. Strong organizational skills with ability to multitask effectively. Proficiency in EHR systems and Microsoft Office Suite. Ability to lift up to 25 pounds, stand for extended periods, and work in mobile clinic environments. Competencies Patient-Centered Care – Provides respectful, compassionate, and high-quality service. Team Collaboration – Works effectively with clinical, administrative, and mobile operations staff. Adaptability – Demonstrates flexibility to changing schedules, patient needs, and mobile operations. Safety & Compliance – Upholds clinical quality, safety, and regulatory standards. Schedule & Work Hours Full-Time: 36 hours per week Flexible schedule required based on community events and mobile unit deployment (occasional evenings or weekends) Additional Job Description Graduate from an accredited Practical Nurse program with six months of patient care experience required. Licensed as an LPN within the state of South Carolina or a compact state. A current CPR card is required; either an American Heart Association Basic Life Support (BLS) for Healthcare Providers card or an American Red Cross Professional Rescuer card. Ability to demonstrate commitment to patient centered care philosophy as evidenced by effective communications skills, professional demeanor, and excellent interpersonal skills. Ability and motivation to articulate and support departmental philosophy of excellent guest relations. Must communicate effectively both verbally and in writing. Must be computer literate. Current American Heart Association (AHA) Basic Life Support (BLS) certification or American Red Cross BLS for Healthcare Providers certification is required If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
RN Infusion Oncology Outpatient Full-time
MUSC

Registered Nurse PRN | Oncology & Infusion Clinic

MUSC Lancaster, SC
Job Description Summary Be part of something meaningful from the ground up. Our newly opened Hematology & Oncology Clinic is looking for a compassionate, detail-oriented Registered Nurse (RN) who wants to make a real difference in patients’ lives while helping shape a growing practice. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ PRN Cost Center CC005634 LAN - Hematology Oncology Outpatient Clinic (LMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 8 Work Shift Job Description Why Join Us? Work in a specialty clinic focused on patient-centered cancer care Be part of a collaborative, supportive team Make lasting connections with patients during their treatment journey Position Highlights Provide high-quality nursing care to hematology and oncology patients Support providers with clinical procedures and patient education Assist with care coordination and ensure a compassionate patient experience Maintain accurate documentation and adhere to safety standards Education: Graduate from an accredited school of nursing License and Certifications: Current South Carolina or compact state Registered Nurse license is required. Current Basic Life Support (BLS) with the American Heart Association (AHA) is required Additional Job Description Bachelor of Nursing degree preferred. RN staff hired on or after July 1, 2013 with an Associate or Diploma degree in nursing are required to be enrolled in an accredited BSN program within two years and successfully obtain a BSN degree within four years of the RN hire or reclassification date. Refer to policy A141 for more details. A minimum of one year of work experience as a registered nurse required. Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current American Heart Association (AHA) Basic Life Support (BLS) certification or American Red Cross BLS for Healthcare Providers certification is required If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
RN Full-time
MUSC

Registered Nurse II - 3W Interventional Cardiology

MUSC Charleston, SC
Job Description Summary Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000452 CHS - ART 3West Acute Cardiology (ART) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Nights (United States of America) Job Description Entity/Organization: MUHA (Medical University Hospital Authority/Medical Center) Hours Per Week: 36 Scheduled Work Hours/Shift: 3 - 12 Hour night shifts per week, including some weekends. Job Summary/Purpose: Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Minimum Training and Education: Bachelor of Nursing degree preferred. RN staff hired on or after July 1, 2013 with an Associate or Diploma degree in nursing are required to be enrolled in an accredited BSN program within two years and successfully obtain a BSN degree within four years of the RN hire or reclassification date. Refer to policy A141 for more details. A minimum of one year of work experience as a registered nurse required. Required Licensure, Certifications, Registrations: Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required, either a certification from an American Heart Association (AHA) BLS for Healthcare Providers (or AHA recognized equivalent) or an American Red Cross CPR/AED for Professional Rescuer and Healthcare Provider. Additional Job Description Physical Requirements: Ability to perform job functions while standing. (Continuous) Ability to perform job functions while sitting. (Continuous) Ability to perform job functions while walking. (Continuous) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work outside in temperature extremes. (Infrequent) Ability to work from elevated areas. (Frequent) Ability to work in confined/cramped spaces. (Frequent) Ability to perform job functions from kneeling positions. (Infrequent) Ability to bend at the waist. (Continuous) Ability to twist at the waist. (Frequent) Ability to squat and perform job functions. (Frequent) Ability to perform “pinching” operations. (Frequent) Ability to perform gross motor activities with fingers and hands. (Continuous) Ability to perform firm grasping with fingers and hands. (Continuous) Ability to perform fine manipulation with fingers and hands. (Continuous) Ability to reach overhead. (Frequent) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to use lower extremities for balance and coordination. (Frequent) Ability to reach in all directions. (Continuous) Ability to lift and carry 50 lbs. unassisted. (Infrequent) Ability to lift/lower objects 50 lbs. from/to floor from/to 36 inches unassisted. (Infrequent) Ability to lift from 36" to overhead 25 lbs. (Infrequent) Ability to exert up to 50 lbs. of force. (Frequent) Examples include: To transfer a 100 lb. patient that can not assist in the transfer requires 50 lbs. of force. For every 100 additional pounds, assistance will be required from another healthcare worker. 20 lbs. of force is needed to push a 400 lb. patient in a wheelchair on carpet. 25 lbs. of force is required to push a stretcher with a patient with one hand. Ability to maintain 20/40 vision, corrected, in one eye or with both eyes. (Continuous) Ability to see and recognize objects close at hand or at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to deal effectively with stressful situations. (Continuous) Ability to work rotating shifts. (Frequent) Ability to work overtime as required. (Frequent) Ability to work in a latex safe environment. (Continuous) Ability to maintain tactile sensory functions. (Continuous) (Selected Positions) *Ability to maintain good olfactory sensory function. (Continuous) *(Selected Positions) *Ability to be qualified physically for respirator use, initially and as required. (Continuous) (Selected Positions ) If you like working with energetic enthusiastic individuals, you will enjoy your career with us! The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
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